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		<title>第十四届全国生物医药色谱质谱及相关技术交流会</title>
		<link>http://nikyang.com.cn/news/event-biopharm-chromatography2023/</link>
		
		<dc:creator><![CDATA[angie yu]]></dc:creator>
		<pubDate>Fri, 19 May 2023 04:32:56 +0000</pubDate>
				<category><![CDATA[最新动态]]></category>
		<category><![CDATA[薄层色谱]]></category>
		<category><![CDATA[CAMAG]]></category>
		<category><![CDATA[高效薄层色谱]]></category>
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					<description><![CDATA[<p>色谱质谱专家云集的盛会 本月 5 &#8211; 8 日，两年一届的 [全国生物医药色谱质谱及相关技术交流会] [&#8230;]</p>
<p><a rel="nofollow" href="http://nikyang.com.cn/news/event-biopharm-chromatography2023/">第十四届全国生物医药色谱质谱及相关技术交流会</a>最先出现在<a rel="nofollow" href="http://nikyang.com.cn">实验室自动化应用一致性评价丨香港力扬企业-溶出仪-药物溶出度仪厂家</a>。</p>
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			<h2 class="elementor-heading-title elementor-size-default"> 色谱质谱专家云集的盛会</h2>		</div>
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				<p>本月 5 &#8211; 8 日，两年一届的 [全国生物医药色谱质谱及相关技术交流会]  在云南省普洱市成功召开，吸引超过 400 位来自全国的色质谱技术与应用专家、学者、厂商和用户出席，无论是学者们最近进展的精彩报告，还是仪器厂商们展出的最新技术产品都是一派欣欣向荣的景象，场面非常热闹。</p><p>这次会议由中国化学会色谱专业委员会、北京理化分析测试技术学会北京色谱学会共同主办，并由北京理化分析测试技术学会及云南师范大学承办，<strong>主题为生物医药色谱质谱新时代</strong>，就色谱、质谱与相关技术的基础研究及其在生命科学、生物医药、食品及环境等相关领域中的最新成果进行展示与研讨，以增进生物医药色谱和质谱领域同仁的交流与合作，共同促进生物医药色谱质谱的创新与发展。</p><p>会议设立大会报告、青年论坛等，并设立展区让客户与展商交流最新的生物医药色谱及质谱技术。配合大会主题，力扬的产品经理唐吉鹤女士在会议上发表报告，题为 <strong>[薄层色谱法的全新数字化时代]</strong>，介绍了高效薄层色谱近 30 年来在国际和国内的发展历程，并分享了国际高效薄层色谱协会和 CAMAG 实验室的最新相关研究成果，令在场听众感到惊喜，报告后多位学者表示惊讶于薄层色谱技术已经发展到如此自动化、高效和多元化的程度，尤其通过近年来 TLC-MS 联用技术的研究热潮和薄层色谱自动化设备的突破性发展，使人们重新注意到高效薄层色谱技术的优势，并且被广泛应用于诸多领域，这其中也包括为生物分析和活性筛选等研究提供了新思路和新方法，迎来了薄层色谱法的全新数字化时代。</p><p> </p>					</div>
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				<p>迎接薄层色谱法的全新数字化时代，力扬全新推出的 CAMAG HPTLC PRO 全自动薄层样品分析及评价系统，能够攻克重现性难题，实现多维检测及提供全方位分析评估，赋能生物医药研发与质控。</p>					</div>
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												<img decoding="async" width="900" height="364" src="http://nikyang.com.cn/wp-content/uploads/2022/09/200721_Camag_HPTLC_PRO.2s.png" class="attachment-large size-large" alt="CAMAG HPTLC PRO" srcset="http://nikyang.com.cn/wp-content/uploads/2022/09/200721_Camag_HPTLC_PRO.2s.png 904w, http://nikyang.com.cn/wp-content/uploads/2022/09/200721_Camag_HPTLC_PRO.2s-300x121.png 300w, http://nikyang.com.cn/wp-content/uploads/2022/09/200721_Camag_HPTLC_PRO.2s-768x311.png 768w" sizes="(max-width: 900px) 100vw, 900px" />														</div>
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		<p><a rel="nofollow" href="http://nikyang.com.cn/news/event-biopharm-chromatography2023/">第十四届全国生物医药色谱质谱及相关技术交流会</a>最先出现在<a rel="nofollow" href="http://nikyang.com.cn">实验室自动化应用一致性评价丨香港力扬企业-溶出仪-药物溶出度仪厂家</a>。</p>
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		<item>
		<title>2023 司徒塔特分子与超分子科学国际研讨会</title>
		<link>http://nikyang.com.cn/news/event-molecular-science2023/</link>
		
		<dc:creator><![CDATA[angie yu]]></dc:creator>
		<pubDate>Wed, 17 May 2023 06:52:44 +0000</pubDate>
				<category><![CDATA[全自动研发方案]]></category>
		<category><![CDATA[最新动态]]></category>
		<category><![CDATA[Chemspeed]]></category>
		<category><![CDATA[自动化合成]]></category>
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					<description><![CDATA[<p>2023 年是司徒塔特分子与超分子科学国际研讨会会议元年，由诺贝尔奖获得者、(美国) 西北大学 J. Fras [&#8230;]</p>
<p><a rel="nofollow" href="http://nikyang.com.cn/news/event-molecular-science2023/">2023 司徒塔特分子与超分子科学国际研讨会</a>最先出现在<a rel="nofollow" href="http://nikyang.com.cn">实验室自动化应用一致性评价丨香港力扬企业-溶出仪-药物溶出度仪厂家</a>。</p>
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				<p>2023 年是司徒塔特分子与超分子科学国际研讨会会议元年，由诺贝尔奖获得者、(美国) 西北大学 J. Fraser Stoddart 院士担任名誉主席、浙江大学黄飞鹤教授担任大会主席，邀请了來自美国、加拿大、德国、新加坡、澳大利亚、以色列等国家和香港等地区的知名学者参会，就超分子组装理论、新型人工分子机器的制备、新组装基元的设计合成、超分子材料的基础与应用拓展等问题展开深入交流与讨论。</p>					</div>
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				<p>会议在本月 1 &#8211; 3  日于杭州萧山浙江大学杭州国际科创中心举行，出席嘉宾包括诺奖、院士在内等 20 余位国外教授，更有来自北京大学、清华大学、浙江大学、上海交通大学等国内高校的 20 余位知名教授作学术报告，吸引超过 300 位观众汇聚一堂，共同思辨探讨。</p>					</div>
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				<p>科技的进步带动新型材料的需求急增，因此创新的自动化、智能化研发及高通量技术在新型材料研发中承担越来越重要的角色。力扬凭借在化学自动化研发领域超过 20 年的专业经验，也借助这次盛大的会议携手 Chemspeed 展示如何在中国新型材料及超分子研发中 “破冰突围”。</p><p>同场，力扬展示 Chemspeed 最新 <a href="http://47.100.44.83/benchtop-solutions/chemspeed/crystal-series/">Crystal Powderdose</a> 全自动固体粉末加样仪，轻巧的机身可同时将天平、机械臂、样品储存罐、多孔板和多规格小瓶放置架等集成在一个小巧平台，节省实验室空间之余，其加样范围精准至亚毫克级别，吸引客户驻足查询。</p>					</div>
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			<h2 class="elementor-heading-title elementor-size-default">Chemspeed 助力实验室材料合成<br>

加速产品研发</h2>		</div>
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				<p>在合成应用领域上，Chemspeed 自动化平台，通过计算模拟和机器学习来进行预测，并挖掘边界条件等信息来获取合适范围内的分子，更借此进行高通量的样品制备、合成、工艺开发、配方、应用或测试，加速产品的研发周期。</p>					</div>
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			<h2 class="elementor-heading-title elementor-size-default">合成效果有目共睹<br>

深得国际机构及大学欢迎</h2>		</div>
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				<section><section><section><h5><a href="https://mp.weixin.qq.com/s?__biz=MzI5NTA1ODkxNw==&amp;mid=2247490392&amp;idx=1&amp;sn=8e8fbfbba4e5c9d4a9e0fa8e3ff7a775&amp;chksm=ec5837d2db2fbec4e32d1b6fa25f77e68aa89e029ba9629af16711c3c3ecab84a8f973a34ecf&amp;scene=21&amp;token=180492050&amp;lang=zh_CN#wechat_redirect"><strong>科莱恩 (</strong>Clariant)</a></h5></section></section></section><section><p>Chemspeed 的 “即插即用” 技术，助力客户从多样性实验中获得灵活的优势，使其研发团队能够快速组装所需的组件和工具以进行所需的实验，高效的实现从项目到项目的对接。</p></section>					</div>
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				<section><section><section><h5><a href="https://mp.weixin.qq.com/s?__biz=MzI5NTA1ODkxNw==&amp;mid=2247490321&amp;idx=1&amp;sn=2cc86059c5cf1fd27796d640f5dc14ef&amp;chksm=ec58379bdb2fbe8dd9e19f04072d28f283c126b495eec384f13c8cd38f527ba084320814cd64&amp;scene=21&amp;token=180492050&amp;lang=zh_CN#wechat_redirect"><strong>澳大利亚国家科学机构联邦科学与工业研究组织 (</strong>CSIRO)</a></h5></section></section></section><section><p>RAMP 研究中心使用 Chemspeed 的 ISYNTH 化合物库全自动合成平台后，仅在 10 天内以 0.5 ~ 1.0克的规格合成了近 1500 种聚合物，研发速度实在令人震惊。</p></section>					</div>
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				<section><section><section><h5><a href="http://47.100.44.83/news/chemspeed-fsu-case-study/"><strong>耶拿大学 (</strong>Friedrich Schiller University Jena)</a></h5></section></section></section><section><p>自动化合成平台使我们能够在时间、速度或聚合物等科学新知识方面获得 5 到 10 倍的提升。结合先进的表征技术，Chemspeed 平台阐明了聚合物结构 &#8211; 性能 &#8211; 关系的关键技术。</p></section>					</div>
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				<section><section><section><h5><a href="http://47.100.44.83/news/ai-hts-smartlab-revolution/"><strong>利物浦大学 (</strong>University of Liverpool)</a></h5></section></section></section><section><p>利物浦大学自主研发的 AI 化学家 (Mobile RoboticChemist)，利用实验室自动化和人工智能的系统，8 天完成 688 次实验，一周时间研究了 1000 种催化配方，并发现了一种新的催化剂。</p></section>					</div>
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		<p><a rel="nofollow" href="http://nikyang.com.cn/news/event-molecular-science2023/">2023 司徒塔特分子与超分子科学国际研讨会</a>最先出现在<a rel="nofollow" href="http://nikyang.com.cn">实验室自动化应用一致性评价丨香港力扬企业-溶出仪-药物溶出度仪厂家</a>。</p>
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		<title>流池法应用培训班     促进技术交流与提升</title>
		<link>http://nikyang.com.cn/news/usp4-training2023/</link>
		
		<dc:creator><![CDATA[angie yu]]></dc:creator>
		<pubDate>Tue, 16 May 2023 06:19:32 +0000</pubDate>
				<category><![CDATA[最新动态]]></category>
		<category><![CDATA[药物研发及检测]]></category>
		<category><![CDATA[Sotax]]></category>
		<category><![CDATA[流池法]]></category>
		<category><![CDATA[溶出度测试]]></category>
		<guid isPermaLink="false">http://47.100.44.83/?p=17502</guid>

					<description><![CDATA[<p>流池法作为中国药典新增溶出测定方法 (第六法) 及美国药典第四法 (USP 4)，由于其独特的流体动力学及溶出 [&#8230;]</p>
<p><a rel="nofollow" href="http://nikyang.com.cn/news/usp4-training2023/">流池法应用培训班     促进技术交流与提升</a>最先出现在<a rel="nofollow" href="http://nikyang.com.cn">实验室自动化应用一致性评价丨香港力扬企业-溶出仪-药物溶出度仪厂家</a>。</p>
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				<p>流池法作为中国药典新增溶出测定方法 (第六法) 及美国药典第四法 (USP 4)，由于其独特的流体动力学及溶出原理，适用的药物剂型范围更广。对于不同晶型、不同粒径的 API，能使用流池法进行表观溶出度测试，对于筛选不同的 API 进行制药有一定的帮助。</p><p>由力扬引进的瑞士 SOTAX CE 7smart 溶出仪，完全符合药典对流池法溶出仪的要求。仪器具有高度的稳定性、准确的流速、精准的温度控制，能得出更精准的药物溶出结果，从而大量节省了研发的时间与人力成本。</p>					</div>
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												<img decoding="async" width="900" height="766" src="http://nikyang.com.cn/wp-content/uploads/2020/09/Sep-20_WeChat1_8-1024x871.jpg" class="attachment-large size-large" alt="SOTAX NIKYANG 力扬 CE7smart" srcset="http://nikyang.com.cn/wp-content/uploads/2020/09/Sep-20_WeChat1_8-1024x871.jpg 1024w, http://nikyang.com.cn/wp-content/uploads/2020/09/Sep-20_WeChat1_8-300x255.jpg 300w, http://nikyang.com.cn/wp-content/uploads/2020/09/Sep-20_WeChat1_8-768x653.jpg 768w, http://nikyang.com.cn/wp-content/uploads/2020/09/Sep-20_WeChat1_8-600x510.jpg 600w, http://nikyang.com.cn/wp-content/uploads/2020/09/Sep-20_WeChat1_8.jpg 1389w" sizes="(max-width: 900px) 100vw, 900px" />														</div>
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			<h2 class="elementor-heading-title elementor-size-default">SOTAX CE 7smart  应用培训班<br>


助力发挥流池法在溶出上的优势</h2>		</div>
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				<p>为了让客户更充分地利用流池法溶出仪，更好地优化项目的实验方案。在 3 月 &#8211; 4 月期间，力扬展开了 7 场关于流池法应用的培训班，邀请了来自全国各地 50 多位客户齐聚深圳、南京，以小组形式开启了沉浸式学习之旅。</p>					</div>
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												<img decoding="async" width="872" height="454" src="http://nikyang.com.cn/wp-content/uploads/2023/05/CE-7smart-Training-2023_1.png" class="attachment-large size-large" alt="" srcset="http://nikyang.com.cn/wp-content/uploads/2023/05/CE-7smart-Training-2023_1.png 872w, http://nikyang.com.cn/wp-content/uploads/2023/05/CE-7smart-Training-2023_1-300x156.png 300w, http://nikyang.com.cn/wp-content/uploads/2023/05/CE-7smart-Training-2023_1-768x400.png 768w" sizes="(max-width: 872px) 100vw, 872px" />														</div>
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												<img decoding="async" width="900" height="577" src="http://nikyang.com.cn/wp-content/uploads/2023/05/Speakers.jpg" class="attachment-large size-large" alt="" srcset="http://nikyang.com.cn/wp-content/uploads/2023/05/Speakers.jpg 925w, http://nikyang.com.cn/wp-content/uploads/2023/05/Speakers-300x192.jpg 300w, http://nikyang.com.cn/wp-content/uploads/2023/05/Speakers-768x492.jpg 768w" sizes="(max-width: 900px) 100vw, 900px" />														</div>
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				<p>培训班导师为力扬资深的应用工程师，通过旗下的 SOTAX CE 7smart 流池法溶出仪，与学员进行以下的深入讲解:</p><ul class=" list-paddingleft-1"><li><h6>流池法的基本理论</h6></li><li><h6>仪器操作与验证</h6></li><li><h6>仪器维护与保养</h6></li><li><h6>流池法方法开发要点</h6></li></ul>					</div>
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												<img decoding="async" width="900" height="890" src="http://nikyang.com.cn/wp-content/uploads/2023/05/CE-7smart-Training-2023_3.jpg" class="attachment-large size-large" alt="" srcset="http://nikyang.com.cn/wp-content/uploads/2023/05/CE-7smart-Training-2023_3.jpg 1000w, http://nikyang.com.cn/wp-content/uploads/2023/05/CE-7smart-Training-2023_3-300x297.jpg 300w, http://nikyang.com.cn/wp-content/uploads/2023/05/CE-7smart-Training-2023_3-768x760.jpg 768w" sizes="(max-width: 900px) 100vw, 900px" />														</div>
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				<p>在药物制剂领域上, 也需要进行不同剂型样品的溶出，更好地优化制剂工艺, 因此我们的应用工程师便在会上分享了各剂型在流池法上的应用经验，包括微球、脂质体、纳米混悬剂、凝胶等的应用，展示实验室做过的案例，协助客户打开做流池法实验的思路。在培训里，以水杨酸作为样品，现场跟学员做一趟完整的实验，让大家动手安装一下流通池，加深操作的印象。</p><p>除了进行溶出实验, 我们亦助力客户剖析方法开发的关键因素，让客户明白如何开展预实验、如何设计下一步实验方案，有条理地进行研发项目。</p>					</div>
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				<p>通过这次培训，学员不但切实地把仪器操作上的小细节、平常没有注意到的地方重新学习一下，对顺利开展实验有极大帮助。与此同时，力扬也可以在这个双方交流的机会，更明白客户遇到的难题，针对性地解决他们的问题，达到相辅相成的效果。</p>					</div>
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		<p><a rel="nofollow" href="http://nikyang.com.cn/news/usp4-training2023/">流池法应用培训班     促进技术交流与提升</a>最先出现在<a rel="nofollow" href="http://nikyang.com.cn">实验室自动化应用一致性评价丨香港力扬企业-溶出仪-药物溶出度仪厂家</a>。</p>
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		<title>HPTLC-MS 应用于蛋白质的胰蛋白酶水解物的分析研究</title>
		<link>http://nikyang.com.cn/news/hptlc-protein-case/</link>
		
		<dc:creator><![CDATA[angie yu]]></dc:creator>
		<pubDate>Thu, 04 May 2023 07:16:18 +0000</pubDate>
				<category><![CDATA[最新动态]]></category>
		<category><![CDATA[薄层色谱]]></category>
		<category><![CDATA[CAMAG]]></category>
		<category><![CDATA[高效薄层色谱]]></category>
		<guid isPermaLink="false">http://47.100.44.83/?p=17446</guid>

					<description><![CDATA[<p>近年来，随着薄层板固定相涂层多样化的发展，高效薄层色谱技术被广泛应用于诸多领域，尤其是 TLC-MS 的联用和 [&#8230;]</p>
<p><a rel="nofollow" href="http://nikyang.com.cn/news/hptlc-protein-case/">HPTLC-MS 应用于蛋白质的胰蛋白酶水解物的分析研究</a>最先出现在<a rel="nofollow" href="http://nikyang.com.cn">实验室自动化应用一致性评价丨香港力扬企业-溶出仪-药物溶出度仪厂家</a>。</p>
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				<p>近年来，随着薄层板固定相涂层多样化的发展，高效薄层色谱技术被广泛应用于诸多领域，尤其是 TLC-MS 的联用和商业化设备的日趋成熟，为生物分析研究提供了新的思路。</p>					</div>
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				<section><section><section><h4><strong>研究</strong><strong>目的</strong></h4></section><section><section></section></section></section></section><section><p>本研究将肌红蛋白、细胞色素 C、β-酪蛋白和牛血清蛋白 (BSA) 等蛋白质的胰蛋白酶分解物中的肽通过高效薄层色谱法进行分离，然后通过与 ESI-MS 偶联在薄层板上原位分析，确定序列覆盖率并与液相检测结果进行比较。</p><p><img decoding="async" class="alignnone size-medium wp-image-17449" src="/wp-content/uploads/2023/05/Protein-300x169.jpg" alt="蛋白质" width="300" height="169" srcset="http://nikyang.com.cn/wp-content/uploads/2023/05/Protein-300x169.jpg 300w, http://nikyang.com.cn/wp-content/uploads/2023/05/Protein-768x432.jpg 768w, http://nikyang.com.cn/wp-content/uploads/2023/05/Protein.jpg 900w" sizes="(max-width: 300px) 100vw, 300px" /></p></section>					</div>
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				<section><section><section><h4><strong>研究方法及分析结果</strong></h4></section><section><section></section></section></section></section><section><p>使用一维 HPTLC 最多分离得到 20 个条带，获得非常紧凑的薄层色谱区，这大约是通过胰蛋白酶消化蛋白质样品获得的肽的数量 (例如细胞色素 C 由 104 个氨基酸组成，经过胰蛋白酶消化后形成 17 个肽）。</p></section>					</div>
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										<img decoding="async" width="554" height="198" src="http://nikyang.com.cn/wp-content/uploads/2023/05/HPTLC-一维分离色谱图.jpg" class="attachment-large size-large" alt="" srcset="http://nikyang.com.cn/wp-content/uploads/2023/05/HPTLC-一维分离色谱图.jpg 554w, http://nikyang.com.cn/wp-content/uploads/2023/05/HPTLC-一维分离色谱图-300x107.jpg 300w" sizes="(max-width: 554px) 100vw, 554px" />											<figcaption class="widget-image-caption wp-caption-text">HPTLC 一维分离色谱图： 图 1. 荧光胺显色-366nm；图 2. 茚三酮显色-白光  [样品从左至右分别为：肌红蛋白、细胞色素 C、β-酪蛋白和牛血清蛋白 (BSA)]</figcaption>
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				<p>再进一步薄层展开，通过 HPTLC 二维分离，可以增加被分离物质的数量。由下图可知一维分离色谱可见 11 个分离条带，二维分离色谱可见 17 个分离斑点。</p>					</div>
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										<img decoding="async" width="311" height="251" src="http://nikyang.com.cn/wp-content/uploads/2023/05/HPTLC-二维分离色谱图.jpg" class="attachment-large size-large" alt="" srcset="http://nikyang.com.cn/wp-content/uploads/2023/05/HPTLC-二维分离色谱图.jpg 311w, http://nikyang.com.cn/wp-content/uploads/2023/05/HPTLC-二维分离色谱图-300x242.jpg 300w" sizes="(max-width: 311px) 100vw, 311px" />											<figcaption class="widget-image-caption wp-caption-text">图 3. HPTLC 二维分离色谱图：细胞色素 C</figcaption>
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										<img decoding="async" width="554" height="109" src="http://nikyang.com.cn/wp-content/uploads/2023/05/细胞色素-C-的序列覆盖率.jpg" class="attachment-large size-large" alt="" srcset="http://nikyang.com.cn/wp-content/uploads/2023/05/细胞色素-C-的序列覆盖率.jpg 554w, http://nikyang.com.cn/wp-content/uploads/2023/05/细胞色素-C-的序列覆盖率-300x59.jpg 300w" sizes="(max-width: 554px) 100vw, 554px" />											<figcaption class="widget-image-caption wp-caption-text">表 1. HPTLC / DESI-MS 分析后获得的细胞色素 C 的序列覆盖率</figcaption>
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				<p>序列覆盖率因固定相涂层材料和分离质量而异。应用纤维素板的二维分离，序列覆盖率几乎与 HPLC / ESI-MS 检测的序列覆盖率相当。</p><p>由此可见，HPTLC-MS 非常适合分析简单和中等复杂的肽混合物。HPTLC / MS 联用的一个特点是分离和检测可以各自独立进行，因此基于薄层开放性色谱的特点可以灵活优化分离和衍生化条件，使分离结果得到更多可能。同时薄层板均为一次性使用，可为各种条件优化设计带来极大的便利。</p>					</div>
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				<section><section><section><section><h6>参考资料 </h6></section></section></section></section><section><section><section><h6><em>[1] S. P. Pasilis et al. Anal. Bioanal. Chem. 391 (2008) 317</em></h6><h6><em>[2] S. P. Pasilis et al. J. Mass Spectrom. 43 (2008) 1627</em></h6></section></section></section>					</div>
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				<p>从以上例子可见，高效薄层色谱法，凭着高效、快速、操作简单、结果准确、灵敏度高和重现性好的优势，不单为样品检测带来创新标准，加上近年来发展迅速，配合自动化与数字化技术，更能发挥前所未有的爆发力，深受业界欢迎。</p>					</div>
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											<a href="http://47.100.44.83/benchtop-solutions/camag/hptlc-pro/">
							<img decoding="async" width="900" height="419" src="http://nikyang.com.cn/wp-content/uploads/2022/11/CAMAG-HPTLC-PRO_group.jpg" class="attachment-large size-large" alt="CAMAG HPTLC PRO" srcset="http://nikyang.com.cn/wp-content/uploads/2022/11/CAMAG-HPTLC-PRO_group.jpg 1000w, http://nikyang.com.cn/wp-content/uploads/2022/11/CAMAG-HPTLC-PRO_group-300x140.jpg 300w, http://nikyang.com.cn/wp-content/uploads/2022/11/CAMAG-HPTLC-PRO_group-768x358.jpg 768w" sizes="(max-width: 900px) 100vw, 900px" />								</a>
											<figcaption class="widget-image-caption wp-caption-text">CAMAG HPTLC PRO 全自动高效薄层检测系统</figcaption>
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				<section><p>想了解更多关于高效薄层色谱技术如何在这个全新数字时代尽显实力，力扬企业将会出席在 5 月 5 &#8211; 8 日在云南普洱举行的 [第十四届全国生物医药色谱质谱及相关技术交流会]，分享更多这方面的应用实例，欢迎大家参与，或留言查询。</p></section><section><section><section>报告主题</section></section></section><p><strong style="font-size: 16px;">薄层色谱法的全新数字时代</strong></p><section><section><h6>讲者</h6></section></section><p><strong style="font-size: 16px;">唐吉鹤 </strong><strong style="font-size: 16px;">(力扬企业 – 产品经理)</strong></p><section><section><h6>日期</h6></section></section><p><strong style="font-size: 16px;">2023 年 5 月 6 日</strong></p><section><section><h6>时间</h6></section></section><p><strong style="font-size: 16px;">下午 4:55</strong></p><section><section><h6>分会场 1</h6></section></section><p><strong style="font-size: 16px;">色谱基础和新技术</strong></p>					</div>
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		<p><a rel="nofollow" href="http://nikyang.com.cn/news/hptlc-protein-case/">HPTLC-MS 应用于蛋白质的胰蛋白酶水解物的分析研究</a>最先出现在<a rel="nofollow" href="http://nikyang.com.cn">实验室自动化应用一致性评价丨香港力扬企业-溶出仪-药物溶出度仪厂家</a>。</p>
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		<title>2023 第 1 季 – 季度通讯 &#124; 疫后复苏 再迎机遇</title>
		<link>http://nikyang.com.cn/news/2023-q1-newsletter/</link>
		
		<dc:creator><![CDATA[Ng, Queenie]]></dc:creator>
		<pubDate>Wed, 05 Apr 2023 02:25:00 +0000</pubDate>
				<category><![CDATA[最新动态]]></category>
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					<description><![CDATA[<p>春回大地，疫后新生，拨开云雾，终见光明。随着社会复常，市场日渐回归热闹的盛况，一系列的活动如雨后春笋般如火如荼 [&#8230;]</p>
<p><a rel="nofollow" href="http://nikyang.com.cn/news/2023-q1-newsletter/">2023 第 1 季 – 季度通讯 | 疫后复苏 再迎机遇</a>最先出现在<a rel="nofollow" href="http://nikyang.com.cn">实验室自动化应用一致性评价丨香港力扬企业-溶出仪-药物溶出度仪厂家</a>。</p>
]]></description>
										<content:encoded><![CDATA[
<p>春回大地，疫后新生，拨开云雾，终见光明。随着社会复常，市场日渐回归热闹的盛况，一系列的活动如雨后春笋般如火如荼地进行，力扬也干劲十足，活跃于各大会议及研讨会当中，与业界持续交流。</p>



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<p></p>



<p><strong>IDC2023 <strong>第四届化学创新药与改良型新药研发论坛</strong>（3月）</strong></p>



<p>为响应 “十四五” 医药工业发展规划，论坛于 2023 年 3 月 23 &#8211; 24 日在上海举办，聚焦化学新药创新技术以及热点疾病领域、改良型新药研发前进方向等角度，邀请了 60 多位演讲嘉宾以及 1000 位参会嘉宾共同探讨。力扬企业的业务发展总监 &#8211; 赵宇女士除了应邀在论坛上讲述样品制备自动化的报告外。同时亦应大会的合作媒体 &#8211; 药精通 Bio 讲堂邀请，进行 &#8220;流池法在药物早期研发中的应用&#8221; 的在线直播课堂，为与会者带来不同的研发及检测的知识。课堂回放已上载到力扬微信小程序。欢迎大家随时进入小程序收看。</p>



<figure class="wp-block-image size-full"><img decoding="async" width="999" height="364" src="/wp-content/uploads/2023/04/wechat-mini-app.png" alt="力扬微信小程序" class="wp-image-17435" srcset="http://nikyang.com.cn/wp-content/uploads/2023/04/wechat-mini-app.png 999w, http://nikyang.com.cn/wp-content/uploads/2023/04/wechat-mini-app-300x109.png 300w, http://nikyang.com.cn/wp-content/uploads/2023/04/wechat-mini-app-768x280.png 768w" sizes="(max-width: 999px) 100vw, 999px" /></figure>



<p><strong>CIS-Asia 2023 第十二届化学制药国际峰会-亚洲 (3月)</strong></p>



<p>峰会由百世传媒 (Best Media) 及中国药学会制药工程专业委员会共同主办，3 月 16 &#8211; 17 日在天津举行，聚焦创新药、改良新药和仿制药研发的议题，汇聚 1600 多位业内同仁共商发展大势与技术细节。大会邀来众多专家讲课，力扬企业的业务发展总监 &#8211; 赵宇应邀于会上讲述了 &#8220;样品制备自动化 ——方法转移、验证与法规符合性&#8221;，分享药品质量控制的见解。</p>



<div class="wp-block-image"><figure class="aligncenter size-large"><img decoding="async" width="1024" height="683" src="/wp-content/uploads/2023/04/Event-2023-Q1-01-1024x683.jpg" alt="" class="wp-image-17436" srcset="http://nikyang.com.cn/wp-content/uploads/2023/04/Event-2023-Q1-01-1024x683.jpg 1024w, http://nikyang.com.cn/wp-content/uploads/2023/04/Event-2023-Q1-01-300x200.jpg 300w, http://nikyang.com.cn/wp-content/uploads/2023/04/Event-2023-Q1-01-768x512.jpg 768w, http://nikyang.com.cn/wp-content/uploads/2023/04/Event-2023-Q1-01.jpg 1080w" sizes="(max-width: 1024px) 100vw, 1024px" /></figure></div>



<p></p>



<p><strong>2023 药物化工结晶技术研究暨工艺开发技术应用研讨会 (3月)</strong></p>



<p>为促进国内医药化工结晶技术的研究进程，加快提高我国结晶技术水平，中国化工企业管理协会于 3 月 24 &#8211; 26 日在南京举行会议，参会人员包括从事制药和化工的企业、高等院校、科研院所，从事有机合成、晶型研究、工艺开发、药物研发及质量控制的应用人员等。力扬作为支持单位也派出专家代表 &#8211; 产品经理杜世振博士分享 &#8220;化繁为简 &#8211; 构建自动化结晶研发实验室&#8221; 的报告，介绍前沿的结晶研究技术。</p>



<figure class="wp-block-image size-large"><img decoding="async" width="1024" height="683" src="/wp-content/uploads/2023/04/Event-2023-Q1-02-1024x683.jpg" alt="" class="wp-image-17437" srcset="http://nikyang.com.cn/wp-content/uploads/2023/04/Event-2023-Q1-02-1024x683.jpg 1024w, http://nikyang.com.cn/wp-content/uploads/2023/04/Event-2023-Q1-02-300x200.jpg 300w, http://nikyang.com.cn/wp-content/uploads/2023/04/Event-2023-Q1-02-768x512.jpg 768w, http://nikyang.com.cn/wp-content/uploads/2023/04/Event-2023-Q1-02.jpg 1080w" sizes="(max-width: 1024px) 100vw, 1024px" /></figure>



<p></p>



<p><strong>2023 第十七次全国检验医学学术会议 (3月)</strong></p>



<p>会议在 3 月 30 日 &#8211; 4 月 1 日在长沙国际会议中心召开，由中华医学会、中华医学会检验医学分会主办、湖南省医学会承办。会议涵盖临床检验和实验室管理各领域最新的研究成果和发展趋势，并对检验医学所面临的新形势和新挑战进行广泛充分的交流探讨。力扬派出代表出席，在会场内介绍 CAMAG DBS 全自动干血斑分析系统，分享干血斑技术在治疗药物监测、维生素 D 检测及生物信息研究等的应用。</p>



<p></p>



<p><strong>CDIC2023 第七届中国药品检验技术大会 &#8211; 广州站 (2月)</strong></p>



<p>大会于 2 月 24 – 25 日在广州召开，由广东省药学会主办，超过 400 多位来自制药行的专家，于会上共同探讨质量控制新技术、检验检测新方法，热闹非常。论坛也邀请到中检院及广东、北京、江苏、贵州等省市药检院专家出席会议宣讲，其中力扬企业的业务发展总监 – 赵宇女士也在台上发表报告，分享 “自动化样品制备及方法验证” 的经验。</p>



<p></p>



<p><meta charset="utf-8"><span class="has-inline-color has-vivid-cyan-blue-color"><strong><strong>活动预告</strong></strong></span></p>



<p>力扬在未来将继续在不同的活动频繁露面，期待届时与大家会面交流。</p>



<p><strong>5月：</strong><br><strong>&#8211; 全国生物医药色谱质谱及相关技术交流会 (云南)</strong><br><strong>&#8211; 第十四届化学制药国际峰会 (苏州)</strong></p>



<p><strong>6月：</strong><br><strong>&#8211; CRC 2023 第二届化学药研发与 CMC 论坛 (南京)</strong><br><strong>&#8211; CPHI 2023 第二十一届世界制药原料中国展 (上海)</strong></p>



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<p><a rel="nofollow" href="http://nikyang.com.cn/news/2023-q1-newsletter/">2023 第 1 季 – 季度通讯 | 疫后复苏 再迎机遇</a>最先出现在<a rel="nofollow" href="http://nikyang.com.cn">实验室自动化应用一致性评价丨香港力扬企业-溶出仪-药物溶出度仪厂家</a>。</p>
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		<title>已然启动的科研变革 &#8211; 人工智能 + 高通量实验</title>
		<link>http://nikyang.com.cn/news/ai-hts-smartlab-revolution/</link>
		
		<dc:creator><![CDATA[Ng, Queenie]]></dc:creator>
		<pubDate>Mon, 03 Apr 2023 04:10:00 +0000</pubDate>
				<category><![CDATA[全自动研发方案]]></category>
		<category><![CDATA[最新动态]]></category>
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		<category><![CDATA[高通量筛选]]></category>
		<guid isPermaLink="false">http://47.100.44.83/?p=17419</guid>

					<description><![CDATA[<p>早段时间 ChatGPT 掀起不少声浪，该系统透过 AI 演算学习进行分析，为用户快速寻找答案。近日为了回应市 [&#8230;]</p>
<p><a rel="nofollow" href="http://nikyang.com.cn/news/ai-hts-smartlab-revolution/">已然启动的科研变革 &#8211; 人工智能 + 高通量实验</a>最先出现在<a rel="nofollow" href="http://nikyang.com.cn">实验室自动化应用一致性评价丨香港力扬企业-溶出仪-药物溶出度仪厂家</a>。</p>
]]></description>
										<content:encoded><![CDATA[
<p>早段时间 ChatGPT 掀起不少声浪，该系统透过 AI 演算学习进行分析，为用户快速寻找答案。近日为了回应市场的需求，百度也发布了生成式 AI 产品&nbsp;—— 文心一言。</p>



<p>近年人工智能的应用已经逐渐走进大众的视野，而在科研领域，基于机器学习的人工智能系统也早已被世界知名的科研机构用于协助科学家完成一项又一项艰深的研究，科研模式的变革早已启动。</p>



<p><span class="has-inline-color has-vivid-cyan-blue-color"><strong>AI + 自动化技术</strong>，<strong>深受世界知名科研公司青睐</strong></span></p>



<p></p>



<p><strong>随机森林算法</strong> &#8211; <strong>普林斯顿大学 x&nbsp;默克</strong></p>



<p>早在 2018 年，普林斯顿大学的 Abigail Doyle 教授就与美国默克 (Merck) 的 Spencer Dreher 博士等合作，以机器学习算法 —— 随机森林算法 (Random Forest Algorithm)，加上通过高通量实验获得的过千项数据进行训练，准确预测了多维变量的 Buchwald-Hartwig 偶联反应产率。Buchwald-Hartwig 反应在药物合成中具有广泛的价值，然而，将这一反应应用于复杂的药物大分子仍然具有挑战性，关键在于当中的五元杂环化合物，如异恶唑这些杂环具有类似药物的特性，但合成并不容易，因此研究团队此次对 Buchwald-Hartwig 偶联反应的研究别具意义。</p>



<p>由于反应物的稀缺，以及化学结构和反应的多维性，过往很难产生足够的数据或从数据库中获得足够完整和一致的数据来进行人工智能的算法训练。随着研究维度的加深，要取得有意义的数据便愈加艰难，而在本次的研究当中，十分关键的是研究人员利用了默克公司较早前建立的高通量反应筛选平台，该高通量实验平台可以在一天内进行超过 1500 个反应，每个反应只需用 0.02 毫克的材料，为研究提供了大量完整及准确的数据基础。</p>



<p></p>



<p><strong>Mobile Robotic Chemist</strong> &#8211; <strong>利物浦大学</strong></p>



<p>除了普林斯顿大学与默克公司合作的研究外，在 2020 年登上 《Nature》 封面的利物浦大学自主研发的 AI 化学家 (Mobile Robotic Chemist)，利用实验室自动化和人工智能的系统，8 天完成 688 次实验，一周时间研究了 1000 种催化配方，并发现了一种新的催化剂。</p>



<div class="wp-block-image"><figure class="aligncenter size-large is-resized"><img decoding="async" src="/wp-content/uploads/2022/10/WeChat_Nov-21_2-772x1024.jpg" alt="" class="wp-image-16881" width="772" height="1024" srcset="http://nikyang.com.cn/wp-content/uploads/2022/10/WeChat_Nov-21_2-772x1024.jpg 772w, http://nikyang.com.cn/wp-content/uploads/2022/10/WeChat_Nov-21_2-226x300.jpg 226w, http://nikyang.com.cn/wp-content/uploads/2022/10/WeChat_Nov-21_2-768x1019.jpg 768w, http://nikyang.com.cn/wp-content/uploads/2022/10/WeChat_Nov-21_2.jpg 800w" sizes="(max-width: 772px) 100vw, 772px" /><figcaption><meta charset="utf-8"><em><sub>图片源自网络</sub></em></figcaption></figure></div>



<p></p>



<p><strong>自动化合成平台</strong> &#8211; <strong>麻省理工学院</strong></p>



<p>无独有偶，登上 《Science》 的美国麻省理工学院 (MIT) 研究人员也开发了一种结合 AI 设计合成路线和机器人执行的自动化合成平台。</p>



<p>实验中，利用数据库中的反应训练了人工智能算法，为指定分子提出合成路线，包括反应条件，并根据步骤数量和预测产量来评估哪条路径是最佳。</p>



<p>同时，MIT 研究人员在新开发的系统上结合了三个主要步骤：首先，由人工智能指导的软件提出了合成分子的途径，然后专家化学家审查这条路线并将其细化为化学 “配方”，最后将配方发送到机器人平台，自动组装硬件并执行反应构建分子。</p>



<p>此外，该系统拥有一个灵活的机器人手臂，能够执行所有合成操作流程，实现自动化合成，并成功用于 15 个化学小分子药物的合成路线设计和自动化合成。</p>



<p></p>



<p></p>



<p><strong>RoboRXN &#8211; IBM</strong></p>



<p>IBM 研究中心也与实验室自动化的专业品牌 Chemspeed 合作，建立了以 AI 驱动的 RoboRXN 化学实验室。这一实验室融合了云技术、AI 和自动化高通量实验工作站，改变了化学家的工作方式，极大地加速了研发效率。</p>



<figure class="wp-block-image size-large is-resized"><img decoding="async" src="/wp-content/uploads/2022/10/WeChat_Nov-21_4-1024x526.png" alt="" class="wp-image-16889" width="840" height="431" srcset="http://nikyang.com.cn/wp-content/uploads/2022/10/WeChat_Nov-21_4-1024x526.png 1024w, http://nikyang.com.cn/wp-content/uploads/2022/10/WeChat_Nov-21_4-300x154.png 300w, http://nikyang.com.cn/wp-content/uploads/2022/10/WeChat_Nov-21_4-768x395.png 768w, http://nikyang.com.cn/wp-content/uploads/2022/10/WeChat_Nov-21_4.png 1080w" sizes="(max-width: 840px) 100vw, 840px" /><figcaption><em><sub>图片源自网络</sub></em></figcaption></figure>



<p>以上的研究都说明了人工智能技术在科学研究领域的巨大潜力，但是纵观所有的人工智能在化学研究上的应用案例，无一例外的都离不开自动化实验技术。作为 “硬件设施”，自动化技术执行 AI &nbsp;(“软件”) 提供的最优化实验方案，并提供大量的完整且准确的数据。作为 “软件设施”，人工智能系统可以利用这些数据进行训练及演算，快速预测研究结果，并完成实验的迭代并优化过程，帮助科学家快速找到有价值的研究方向，减少大量的实验时间和研究成本。科研的变革已然启动，未来，人工智能的技術必然将更广泛应用在科学研究领域，推动科学的进步。</p>



<p>想构建可结合人工智能的实验室？欢迎联系力扬，我们会为你提供前沿的实验室解決方案。</p>



<p></p>



<p><sub>参考资料:</sub></p>



<p><em><sub>Ahneman DT, Estrada JG, Lin S, Dreher SD, Doyle AG. Predicting reaction performance in C-N cross-coupling using machine learning. Science. 2018 Apr 13;360(6385):186-190.</sub></em></p>



<p><em><sub>Buitrago Santanilla A, Regalado EL, Pereira T, Shevlin M, Bateman K, Campeau LC, Schneeweis J, Berritt S, Shi ZC, Nantermet P, Liu Y, Helmy R, Welch CJ, Vachal P, Davies IW, Cernak T, Dreher SD. Organic chemistry. Nanomole-scale high-throughput chemistry for the synthesis of complex molecules. Science. 2015 Jan 2;347(6217):49-53.</sub></em></p>



<p><em><sub>http://www.vastprotech.com/news_detail/id/142.html</sub></em></p>



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<p><a rel="nofollow" href="http://nikyang.com.cn/news/ai-hts-smartlab-revolution/">已然启动的科研变革 &#8211; 人工智能 + 高通量实验</a>最先出现在<a rel="nofollow" href="http://nikyang.com.cn">实验室自动化应用一致性评价丨香港力扬企业-溶出仪-药物溶出度仪厂家</a>。</p>
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		<title>实验室的日常，谁来拯救我的 996？</title>
		<link>http://nikyang.com.cn/news/powderdose-lab-996/</link>
		
		<dc:creator><![CDATA[Ng, Queenie]]></dc:creator>
		<pubDate>Fri, 31 Mar 2023 03:14:42 +0000</pubDate>
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<p><a rel="nofollow" href="http://nikyang.com.cn/news/powderdose-lab-996/">实验室的日常，谁来拯救我的 996？</a>最先出现在<a rel="nofollow" href="http://nikyang.com.cn">实验室自动化应用一致性评价丨香港力扬企业-溶出仪-药物溶出度仪厂家</a>。</p>
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<figure class="wp-block-image size-large is-resized"><img decoding="async" src="/wp-content/uploads/2023/03/Wechat-996-03-248x1024.jpeg" alt="" class="wp-image-17413" width="592" height="2445" srcset="http://nikyang.com.cn/wp-content/uploads/2023/03/Wechat-996-03-248x1024.jpeg 248w, http://nikyang.com.cn/wp-content/uploads/2023/03/Wechat-996-03-73x300.jpeg 73w, http://nikyang.com.cn/wp-content/uploads/2023/03/Wechat-996-03-372x1536.jpeg 372w" sizes="(max-width: 592px) 100vw, 592px" /></figure>



<figure class="wp-block-image size-large is-resized"><img decoding="async" src="/wp-content/uploads/2023/03/Wechat-996-04-326x1024.jpeg" alt="" class="wp-image-17414" width="587" height="1844" srcset="http://nikyang.com.cn/wp-content/uploads/2023/03/Wechat-996-04-326x1024.jpeg 326w, http://nikyang.com.cn/wp-content/uploads/2023/03/Wechat-996-04-768x2412.jpeg 768w, http://nikyang.com.cn/wp-content/uploads/2023/03/Wechat-996-04-489x1536.jpeg 489w, http://nikyang.com.cn/wp-content/uploads/2023/03/Wechat-996-04-652x2048.jpeg 652w, http://nikyang.com.cn/wp-content/uploads/2023/03/Wechat-996-04-scaled.jpeg 815w" sizes="(max-width: 587px) 100vw, 587px" /></figure>



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</div>
<p><a rel="nofollow" href="http://nikyang.com.cn/news/powderdose-lab-996/">实验室的日常，谁来拯救我的 996？</a>最先出现在<a rel="nofollow" href="http://nikyang.com.cn">实验室自动化应用一致性评价丨香港力扬企业-溶出仪-药物溶出度仪厂家</a>。</p>
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		<item>
		<title>专家云集，齐聚 CDIC 2023 第七届中国药品检验技术大会</title>
		<link>http://nikyang.com.cn/news/cdic-2023-guangzhou/</link>
		
		<dc:creator><![CDATA[angie yu]]></dc:creator>
		<pubDate>Tue, 28 Feb 2023 09:52:29 +0000</pubDate>
				<category><![CDATA[最新动态]]></category>
		<category><![CDATA[样品前处理]]></category>
		<category><![CDATA[CAMAG]]></category>
		<category><![CDATA[Sotax]]></category>
		<guid isPermaLink="false">http://47.100.44.83/?p=17359</guid>

					<description><![CDATA[<p>春回大地，疫情的阴霾终见消失。在 2 月 24 – 25 日，由广东省药学会主办，广东省药学会制药工程专业委员 [&#8230;]</p>
<p><a rel="nofollow" href="http://nikyang.com.cn/news/cdic-2023-guangzhou/">专家云集，齐聚 CDIC 2023 第七届中国药品检验技术大会</a>最先出现在<a rel="nofollow" href="http://nikyang.com.cn">实验室自动化应用一致性评价丨香港力扬企业-溶出仪-药物溶出度仪厂家</a>。</p>
]]></description>
										<content:encoded><![CDATA[		<div data-elementor-type="wp-post" data-elementor-id="17359" class="elementor elementor-17359" data-elementor-settings="[]">
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				<p>春回大地，疫情的阴霾终见消失。在 2 月 24 – 25 日，由广东省药学会主办，广东省药学会制药工程专业委员会、广东省药学会生物医药分析专业委员会和杭州奇易科技有限公司承办的 “第七届中国药品检验技术大会”，在广州保利假日酒店成功召开，并再次看到盛况空前的场面，热闹非常。</p><p>在广东省药学会的大力支持下，会议上吸引超过 400 多位来自省内外的制药企业、药品检测机构和行业专家，共同探讨了质量控制新技术、检验检测新方法，让一众观众及嘉宾学习到新的专业知识，获益良多。</p>					</div>
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										<img decoding="async" width="900" height="675" src="http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_2-1024x768.jpg" class="attachment-large size-large" alt="" srcset="http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_2-1024x768.jpg 1024w, http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_2-300x225.jpg 300w, http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_2-768x576.jpg 768w, http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_2-1536x1152.jpg 1536w, http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_2-2048x1536.jpg 2048w" sizes="(max-width: 900px) 100vw, 900px" />											<figcaption class="widget-image-caption wp-caption-text">会上聚集了众多制药行业的老师及专业人员。</figcaption>
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										<img decoding="async" width="900" height="675" src="http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_5-1024x768.jpg" class="attachment-large size-large" alt="" srcset="http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_5-1024x768.jpg 1024w, http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_5-300x225.jpg 300w, http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_5-768x576.jpg 768w, http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_5-1536x1152.jpg 1536w, http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_5-2048x1536.jpg 2048w" sizes="(max-width: 900px) 100vw, 900px" />											<figcaption class="widget-image-caption wp-caption-text">客户纷纷向产品专员请教关于 SOTAX、  CAMAG 等产品技术的优势，实时互动交流。</figcaption>
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				<p>这次论坛邀请到中检院及广东、北京、江苏、贵州等省市药检院专家出席会议宣讲，其中力扬企业亦获邀出席，不单在现场介绍旗下的 SOTAX、CAMAG 等药品检测解决方案，我们的业务发展总监 – 赵宇女士也在台上发表报告，分享 “自动化样品制备及方法验证” 的经验。</p>					</div>
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												<img decoding="async" width="900" height="534" src="http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_8-1024x608.jpg" class="attachment-large size-large" alt="" srcset="http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_8-1024x608.jpg 1024w, http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_8-300x178.jpg 300w, http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_8-768x456.jpg 768w, http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_8-1536x911.jpg 1536w, http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_8-2048x1215.jpg 2048w" sizes="(max-width: 900px) 100vw, 900px" />														</div>
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										<img decoding="async" width="900" height="636" src="http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_6-1024x724.jpg" class="attachment-large size-large" alt="" srcset="http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_6-1024x724.jpg 1024w, http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_6-300x212.jpg 300w, http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_6-768x543.jpg 768w, http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_6-1536x1086.jpg 1536w, http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_6-2048x1448.jpg 2048w" sizes="(max-width: 900px) 100vw, 900px" />											<figcaption class="widget-image-caption wp-caption-text">业务发展总监 – 赵宇在台上报告。</figcaption>
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												<img decoding="async" width="900" height="675" src="http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_7-1024x768.jpg" class="attachment-large size-large" alt="" srcset="http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_7-1024x768.jpg 1024w, http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_7-300x225.jpg 300w, http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_7-768x576.jpg 768w, http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_7-1536x1152.jpg 1536w, http://nikyang.com.cn/wp-content/uploads/2023/02/第七届中国药品检验技术大会_7-2048x1536.jpg 2048w" sizes="(max-width: 900px) 100vw, 900px" />														</div>
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				<p>随着政策及 《中国药典》 的不断革新，市场上对药品实验室的要求日益提高，业内更多的交流可以促进行业成长的动力，力扬在 3 月份会继续出席更多制药方面的会议，祈望与大家见面。</p>					</div>
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			<h2 class="elementor-heading-title elementor-size-default">CIS-Asia 2023 <br>
第十二届化学制药国际峰会 - 亚洲<br>
3 月 16 – 17 日, 天津</h2>		</div>
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			<h2 class="elementor-heading-title elementor-size-default">IDC 2023 第四届化学创新药与改良型新药研发论坛 <br>
3 月 23 – 24 日, 上海</h2>		</div>
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			<h2 class="elementor-heading-title elementor-size-default">2023 药物化工结晶技术研究暨工艺开发技术应用交流研讨会<br>
3 月 25 – 26 日, 南京</h2>		</div>
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		<p><a rel="nofollow" href="http://nikyang.com.cn/news/cdic-2023-guangzhou/">专家云集，齐聚 CDIC 2023 第七届中国药品检验技术大会</a>最先出现在<a rel="nofollow" href="http://nikyang.com.cn">实验室自动化应用一致性评价丨香港力扬企业-溶出仪-药物溶出度仪厂家</a>。</p>
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		<title>拆解 Procos 加速 API 工艺开发的秘笈</title>
		<link>http://nikyang.com.cn/automated-solution/procos-case/</link>
		
		<dc:creator><![CDATA[angie yu]]></dc:creator>
		<pubDate>Wed, 22 Feb 2023 03:06:59 +0000</pubDate>
				<category><![CDATA[全自动研发方案]]></category>
		<category><![CDATA[最新动态]]></category>
		<category><![CDATA[药物研发及检测]]></category>
		<category><![CDATA[Chemspeed]]></category>
		<category><![CDATA[药物研发]]></category>
		<category><![CDATA[高通量筛选]]></category>
		<guid isPermaLink="false">http://47.100.44.83/?p=17336</guid>

					<description><![CDATA[<p>原料药在医药产业中各个环节中都十分关键，尤其在项目进入临床阶段后，对原料药的需求更大。原料药的生产过程十分复杂 [&#8230;]</p>
<p><a rel="nofollow" href="http://nikyang.com.cn/automated-solution/procos-case/">拆解 Procos 加速 API 工艺开发的秘笈</a>最先出现在<a rel="nofollow" href="http://nikyang.com.cn">实验室自动化应用一致性评价丨香港力扬企业-溶出仪-药物溶出度仪厂家</a>。</p>
]]></description>
										<content:encoded><![CDATA[		<div data-elementor-type="wp-post" data-elementor-id="17336" class="elementor elementor-17336" data-elementor-settings="[]">
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				<p>原料药在医药产业中各个环节中都十分关键，尤其在项目进入临床阶段后，对原料药的需求更大。原料药的生产过程十分复杂，而且容易受环境参数如: 温度、湿度、压力等等的影响，有些原材料更有一定危险性，因此在进行原料药的扩大工艺时，除了要考虑其质量、经济效益外，更要考虑其安全性。通过反应筛选进行原料药的工艺开发，可以寻找最佳的反应条件、最佳的催化体系，实现反应选择性的优化，并获得尽可能低的杂质含量目标产物。</p>					</div>
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			<h2 class="elementor-heading-title elementor-size-default">原料药<br>工艺开发&nbsp;</h2>		</div>
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												<img decoding="async" width="740" height="400" src="http://nikyang.com.cn/wp-content/uploads/2023/02/API_875_main.jpg" class="attachment-full size-full" alt="API" srcset="http://nikyang.com.cn/wp-content/uploads/2023/02/API_875_main.jpg 740w, http://nikyang.com.cn/wp-content/uploads/2023/02/API_875_main-300x162.jpg 300w" sizes="(max-width: 740px) 100vw, 740px" />														</div>
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				<p>为了应对以上的挑战，Procos S.p.A 公司去年年初就正式宣布应用 Chemspeed 自动研发系统，作为研发团队使用的工具，以优化支持 NDA (New Drug Application &#8211; 新药申请) 项目的工作速度。</p><p>Procos S.p.A 公司是一家合同开发机构 (CDMO)，从事活性药物成分 (API)、高级中间体和相关服务的开发、放大和生产。</p>					</div>
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				<h6><strong>Procos S.p.A  </strong>公司透露</h6><p>&#8220;借助 Chemspeed 这项先进的技术，将进一步提高 API 开发和提交给相关监管机构 (如 FDA) 的时间。此外，它还将加快新药申请的时间表、增加试验的数量，以及报告遵循行业指南的数据，包括 21 CFR 第 11 部分。&#8221;</p>					</div>
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										<img decoding="async" width="900" height="676" src="http://nikyang.com.cn/wp-content/uploads/2023/02/CHEMSPEED-1536x1153-1-1024x769.jpg" class="attachment-large size-large" alt="Procos S.P.A 引入 Chemspeed 自动研发系统" srcset="http://nikyang.com.cn/wp-content/uploads/2023/02/CHEMSPEED-1536x1153-1-1024x769.jpg 1024w, http://nikyang.com.cn/wp-content/uploads/2023/02/CHEMSPEED-1536x1153-1-300x225.jpg 300w, http://nikyang.com.cn/wp-content/uploads/2023/02/CHEMSPEED-1536x1153-1-768x577.jpg 768w, http://nikyang.com.cn/wp-content/uploads/2023/02/CHEMSPEED-1536x1153-1.jpg 1536w" sizes="(max-width: 900px) 100vw, 900px" />											<figcaption class="widget-image-caption wp-caption-text">Procos S.p.A 公司引入的 Chemspeed 自动研发系统</figcaption>
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				<p>Chemspeed 为 Procos S.p.A 公司定制的自动化方案 –  Chemspeed Autoplant Prores 系统。它拥有 12 个独立的工艺开发反应釜，每个反应釜有独立温控以及搅拌速度等单独条件的控制，反应釜可以耐 100bar 的压力，最高使用温度为 250℃。在如此高水平的自动化技术协助下，<strong>催化系统筛选、温度、压力和反应量或优化设计的实验几天就能完成</strong><strong>，亦可进行重复实验来评估实验的可变性。</strong></p>					</div>
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										<img decoding="async" width="522" height="397" src="http://nikyang.com.cn/wp-content/uploads/2023/02/Chemspeed-Autoclaves.jpg" class="attachment-full size-full" alt="Chemspeed 工艺开发反应釜" srcset="http://nikyang.com.cn/wp-content/uploads/2023/02/Chemspeed-Autoclaves.jpg 522w, http://nikyang.com.cn/wp-content/uploads/2023/02/Chemspeed-Autoclaves-300x228.jpg 300w" sizes="(max-width: 522px) 100vw, 522px" />											<figcaption class="widget-image-caption wp-caption-text">Chemspeed 工艺开发反应釜</figcaption>
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			<h2 class="elementor-heading-title elementor-size-default">应用与效益</h2>		</div>
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				<h4>1. 高通量反应筛选</h4><p>Procos 使用 Chemspeed Autoplant Prores 系统进行了一个高通量反应筛选的 DoE，研究了不同变量对一个对映选择性 SN2 反应结果的影响，即通过 D-Optimal Design，同时研究三个多层次的定性变量 ＋ 一个定量变量，从而在 250 多个可能组合中选择了 40 个实验 (+8 个重复) 进行实验。</p><p> </p>					</div>
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										<img decoding="async" width="290" height="496" src="http://nikyang.com.cn/wp-content/uploads/2023/02/Procos-SN2-案例研究.jpg" class="attachment-full size-full" alt="Procos SN2 案例研究" srcset="http://nikyang.com.cn/wp-content/uploads/2023/02/Procos-SN2-案例研究.jpg 290w, http://nikyang.com.cn/wp-content/uploads/2023/02/Procos-SN2-案例研究-175x300.jpg 175w" sizes="(max-width: 290px) 100vw, 290px" />											<figcaption class="widget-image-caption wp-caption-text">Procos SN2 案例研究: 反应方案 (顶部)，  变量表 (中)，影响对映体过量的变量的测定 (下)</figcaption>
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				<h5><strong>筛选结果</strong></h5><p>对映体过量最有影响的因素为: 化合物 A、4 号碱、2 号溶剂、较低的反应温度值。</p>					</div>
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				<h4>2. 对映选择性氢化反应</h4><p>Procos 公司进行了另一个对映选择性氢化反应的研究，通过面中心复合设计 (Face Centered Central Composite Design) 在 3 级 4 个变量 ＋ 3 个中心点规划一组 27 个反应，对对映体过量成功进行了优化。</p>					</div>
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										<img decoding="async" width="441" height="507" src="http://nikyang.com.cn/wp-content/uploads/2023/02/Procos-氢化案例研究.jpg" class="attachment-large size-large" alt="Procos 氢化案例研究" srcset="http://nikyang.com.cn/wp-content/uploads/2023/02/Procos-氢化案例研究.jpg 441w, http://nikyang.com.cn/wp-content/uploads/2023/02/Procos-氢化案例研究-261x300.jpg 261w" sizes="(max-width: 441px) 100vw, 441px" />											<figcaption class="widget-image-caption wp-caption-text">Procos 氢化案例研究：反应方案 (顶部)，PAR 定义 (中间)，三维图表归纳催化剂、温度和对映体过量。</figcaption>
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				<p>以上 Procos 的实验过程都在 Chemspeed 自动化研发平台上进行，所有的实验数据都被完整记录，包括：温度、压力、配料率、搅拌时间、转速等等，可用于进一步的评估及溯源。</p><p>与传统的实验方法相比，应用自动化研发系统使研究人员能够在更短时间内完成化学工艺的研究，完成工艺优化，大大提升其产出率。同时，全流程的自动化亦很大程度上降低了处理化学成份时对科研人员的危害。</p>					</div>
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				<p><em>参考资料：</em></p><p><em>1. PROCOS S.p.A, Feb 1 2022, PROCOS SPA Announces the Launch of CHEMSPEED Automation Technology (Press Release), <a href="http://www.procos.it.">www.procos.it.</a> </em></p><p><em>2. </em><em>Mr. Simone Manzini, Mr. Paolo Paissoni (2022), </em><em>A modern tool to accelerate Process Development to match the customer&#8217;s timeline, PROCOS R&amp;D Lab Automation, <a href="http://www.procos.it.">www.procos.it.</a></em></p>					</div>
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		<p><a rel="nofollow" href="http://nikyang.com.cn/automated-solution/procos-case/">拆解 Procos 加速 API 工艺开发的秘笈</a>最先出现在<a rel="nofollow" href="http://nikyang.com.cn">实验室自动化应用一致性评价丨香港力扬企业-溶出仪-药物溶出度仪厂家</a>。</p>
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		<title>2022 第 4 季 – 季度通讯 &#124; 新岁启封 万象更新</title>
		<link>http://nikyang.com.cn/news/2022-q4-newsletter/</link>
		
		<dc:creator><![CDATA[Ng, Queenie]]></dc:creator>
		<pubDate>Thu, 29 Dec 2022 08:37:16 +0000</pubDate>
				<category><![CDATA[最新动态]]></category>
		<guid isPermaLink="false">http://47.100.44.83/?p=17199</guid>

					<description><![CDATA[<p>2022 年已经来到尾声，随着近日的防疫限制日渐解除，相信下一年度会万象更新，迎来更美好的一年，力扬企业也期待 [&#8230;]</p>
<p><a rel="nofollow" href="http://nikyang.com.cn/news/2022-q4-newsletter/">2022 第 4 季 – 季度通讯 | 新岁启封 万象更新</a>最先出现在<a rel="nofollow" href="http://nikyang.com.cn">实验室自动化应用一致性评价丨香港力扬企业-溶出仪-药物溶出度仪厂家</a>。</p>
]]></description>
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<p><br>2022 年已经来到尾声，随着近日的防疫限制日渐解除，相信下一年度会万象更新，迎来更美好的一年，力扬企业也期待在下年度继续为大家提供专业优质的服务。</p>



<p>在此回顾一下今年最后一个季度的活动，同时也祝大家新年快乐，2023 年事事顺心！</p>



<p></p>



<h2 class="wp-block-heading"><span class="has-inline-color has-vivid-cyan-blue-color">力扬微信小程序 &#8211; 力扬科研实验室信息中心</span> <span class="has-inline-color has-vivid-cyan-blue-color">正式开通</span></h2>



<p>力扬最新的微信小程序已经投入服务了，大家可于微信上随时重温我们的会议内容，更多的产品及技术信息将会陆续分享到平台上，紧贴我们了解最新前沿信息。</p>



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<h2 class="wp-block-heading"><span class="has-inline-color has-vivid-cyan-blue-color"><strong>2022 年北京药学年会</strong> (12月)</span></h2>



<p>第 24 届北京药学年会于 12 月 17 – 18 日以线上形式召开。举行了二十多届的药学年会一如以往，汇集了政府部门、科研院所、医药企业、医疗机构广大医药工作者进行分享及交流。由于疫情关系，这次会议移师至线上举行，吸引了超过 23 万人次观看，并累计进行了 70 小时报告。力扬的专家，业务发展总监 &#8211; 赵宇女士也受邀于会上分享<strong>&nbsp;[流通法溶出仪在特殊制剂的应用]</strong>，大家可以在微信小程式回顾。</p>



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<h2 class="wp-block-heading"><span class="has-inline-color has-vivid-cyan-blue-color">第 88 届 API China 《中国药典》药品检验技术 应用及发展研讨会</span> <meta charset="utf-8"><span class="has-inline-color has-vivid-cyan-blue-color">(12月)</span></h2>



<p>研讨会于 12 月 6 – 8 日举行，会议邀请了药典委员会委员、资深顾问及行业专家，就 《中国药典》 药品检验分析方法研究进展、方法学研究、检验方法适用性验证等进行深入解读和经验分享，并从先进分析检测技术方面在药品质控的研究和应用进行探讨、更因应药典通用检验方法应用中存在的问题进行现场交流和解答。力扬的产品专家唐吉鹤老师受邀于会议中演讲<strong>&nbsp;[薄层色谱法如何真正 “高效”]</strong>。大家可以在微信小程式回顾。</p>



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<p><a rel="nofollow" href="http://nikyang.com.cn/news/2022-q4-newsletter/">2022 第 4 季 – 季度通讯 | 新岁启封 万象更新</a>最先出现在<a rel="nofollow" href="http://nikyang.com.cn">实验室自动化应用一致性评价丨香港力扬企业-溶出仪-药物溶出度仪厂家</a>。</p>
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